Chin up Gemm. It took a long time to create you stash of fabric, projects and materials. It will take time to get it all back in an order that will work for you. Recognizing that you need to reassess your work area is HUGE . For my two cents, I would suggest that you dive into what you use the most and keep just that limited amount in order and close at hand.so you can tackle some of your projects and experience the joy of creating what makes you happy.
My experience has been than when I try to organize the whole room that I get bogged down and discouraged. For me, I go space by space a little at a time and that seems to satisfy me. Over time, my space though not perfect like in magazines or online, but I can find my favorite rulers and the little scissors that I adore. I am pleased with my progress and it looks and feels better than a few months ago.