One thing I have found very helpful is having a design wall right beside my sewing machine, really helpful if you are making a complicated block or a one block wonder/kaleidoscope block.
I am able to set up such that when sitting at my machine I have a pressing station on my right (one was made locally by the spouse of a quilt shop owner that clamps onto the table I use for the sewing machine...what a lifesaver that little pressing station has been!) and on my left is a wall on which I have put up a big piece of black batting.
I can sit and fiddle with the block pieces on the design wall, sew them up, press them and put them back in place without having to carry them over to a wall...in which case the chance of error increases exponentially! It is just too easy to get back to the machine and sew the wrong sides together...
I do move around a lot between the main design wall, pressing table and cutting table, but when doing a fiddly bit, this all-in-one-place setup works very well to reduce unsewing events!