For me, getting rid of books, fabric, thread, art supplies, jewelry making supplies, cool stuff that could be useful someday and tools is very difficult. Every time I've decided to do a major purge, I end up getting rid of clothes and keeping all the stuff listed above. All my clothes now fit into one small 19th century wardrobe and a small dresser and I'm down to 5 pairs of shoes. But my art supplies, books, quilting supplies etc. take up two whole rooms and part of the garage LOL.
Rob