The biggest change for me is that I have gone from "planned" quilts using a controlled set of 3-5 fabrics to scrappy projects using multiple different fabrics for each shade or value.
Most of my work is still "contemporary adaptations of traditional blocks" but I do a lot more contemporary all over designs like jelly roll race or combinations of squares and rectangles like the 3- and 5- yard quilts. I'm not quite loosened up enough to be an improv quilter but I'm willing to put a lot more chance and randomness into my projects.
Even bigger changes, however, are construction techniques. I started before the rotary revolution. Pre-rulers I did figure out I could use blotter sized quad grid paper to scissor cut more than one layer at a time. Some of the techniques I use happily today (like using two squares and sewing along the diagonal to make a HST) I used to sniff at and call them "fabric wasteful techniques". I've gone from being very precise with measuring and piecing to cutting large and trimming down -- and my end results are actually more precise.