I can't wait to see the finished product. I'm not an expert but I don't see why you can't use different techniques. Years ago I used quickie panels, piecing, tying and hand quilting all on one quilt and it really looked good. (even if I do say so myself)
Gal's right though, if it's going to be used on a bed keep the embellishments to a minimum. If it's to be a wall hanging the skies the limit.
As a person that grew up watching Sgt. Preston of the Royal Canadian Mounted Police, I really enjoyed the story of your grandfather. I loved that show as a child.