Yup, you sure can. I have the 6600 and I use big cones all the time.

I put the largest spool caps on the base of the spool pins like platforms, so they don't wobble as much. I know you can get thicker pins for large cones but I never have bothered. The cone tends to rock a little bit sometimes but it doesn't seem to harm anything - stitches still come out beautifully and I don't get any breakage, etc.

If that doesn't seem to work for you and you don't have a cone holder, drop the cone into a can behind your machine and thread it normally. That metal arm that the thread goes through first is essentially the same as the top of a cone holder so you should be able to get away with that.

You can place a coffee cup behind your machine to use as a cone holder, works great

Thanks for your replies!! I knew you guys would know!

I also own a Janome 6600. I set my cones from Connecting Threads in a little tin bucket that I picked up at The Dollar Spot at Target. Simple solution and more portable when I want to travel with my machine.

You should be able to use a container behind your machine to hold the spool. Thread machine as usual.

I have a Singer and I use a travel coffee mug as an upright thread holder for the large spools or cones. It works beautifully. I put thread through the little air hole in top of lid and set it behind my machine. Then thread the machine as usual.

Hubby made me a thread stand and I also use a very heavy large beer glass.

I made one from an old wooden paper towel holder, most of my thread fits on it. At some point I will get my DH to sand the dowel down so all my spools will fit.

I use a wide mouth pint or quart jar, works fine for me.

http://www.ebay.com/itm/Universal-TH...item417fe09ed7 I don't understand this one. The thread needs to come off the spool from the top, even is it is lying on its side. If it doesn't come off the top, you will get extra pull, and extra tension, when the thread comes off the back side of the cone.

I have a cone holder like this http://www.ebay.com/sch/i.html?_nkw=cone+thread+stand and also use a recipe card holder my nephew made for me. The cone sits at a slant and the thread comes off the top of the cone and up to the first thread guide on the machine.